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Endocrine-Adrenal.html
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Endocrine-Adrenal.html
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<!DOCTYPE html PUBLIC "-//W3C//DTD XHTML 1.0 Transitional//EN" "http://www.w3.org/TR/xhtml1/DTD/xhtml1-transitional.dtd">
<html>
<html xmlns="http://www.w3.org/1999/xhtml">
<head>
<meta http-equiv="Content-Type" content="text/html; charset=UTF-8">
<title>Adrenal carcinoma</title>
<link rel="stylesheet" type="text/css" href="view.css" media="all">
<script type="text/javascript" src="view.js"></script>
<script>
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<style>
table, th, td {
border: 1px solid silver;
border-collapse: collapse;
padding: 4px;
}
</style>
</head>
<body>
<img id="top" src="top.png" alt="">
<div id="form_container">
<div class="form_description">
<h2>
<a href=".\cap\Cancer-Protocols-2023-03-Update\Endocrine Protocol Folder\Adrenal_4.3.1.0.REL_CAPCP.pdf" target="_blank">
<div class="tooltip">
Carcinoma of the adrenal gland
<span class="tooltiptext">click to access explanations in the original CAP template</span>
</div>
<a>
</h2>
</div>
<form>
<p>
<fieldset style="border-color:#e6e6ff;">
<legend><label class="description">Gross descriptions:</label></legend>
<p>
<table border="1">
<col width="55%">
<tr>
<td>
<label class="description">- Procedure:</label>
</td>
<td>
<select class="element select large" ID="A01">
<option value=""></option>
<option value=" - Percutaneous needle biopsy">Percutaneous needle biopsy</option>
<option value=" - Endoscopic directed biopsy (specify radiographic technique):">Endoscopic directed biopsy (specify radiographic technique):</option>
<option value=" - Adrenalectomy, total">Adrenalectomy, total</option>
<option value=" - Adrenalectomy, partial">Adrenalectomy, partial</option>
<option value=" - Other (specify):">Other (specify):</option>
<option value=" - Not specified">Not specified</option>
</select>
</td>
</tr>
<tr>
<td>
<label class="description">- Tumor laterality:</label>
</td>
<td>
<select class="element select large" ID="A02">
<option value=""></option>
<option value=" - Right">Right</option>
<option value=" - Left">Left</option>
<option value=" - Bilateral">Bilateral</option>
<option value=" - Other (specify):">Other (specify):</option>
<option value=" - Not specified">Not specified</option>
</select>
</td>
</tr>
<tr>
<td>
<label class="description">- Tumor size:</label>
</td>
<td>
<select class="element select large" ID="A03">
<option value=""></option>
<option value=" - Greatest dimension (mm): ">Greatest dimension (mm): </option>
<option value=" - All dimensions (mm x mm x mm): ">All dimensions (mm x mm x mm):</option>
<option value=" - Cannot be determined (explain): ">Cannot be determined (explain):</option>
</select>
</td>
</tr>
<tr>
<td>
<label class="description">- Tumor weight (whole gland incluidng tumor):</label>
</td>
<td>
<input type="text" class="element text large" ID="A04" size="5">
</td>
</tr>
<tr>
<td valign="top">
<label class="description">- Tumor description:</label>
</td>
<td>
<input class="element checkbox" type="checkbox" id="A05" value=" - Hemorrhagic"><label >Hemorrhagic</label><br>
<input class="element checkbox" type="checkbox" id="A06" value=" - Necrotic"><label >Necrotic</label><br>
<input class="element checkbox" type="checkbox" id="A07" value=" - Other (specify):"><label >Other (specify):</label><br>
</td>
</tr>
</table>
</p>
</fieldset>
</p>
<p>
<fieldset style="border-color:#e6e6ff;">
<legend><label class="description">Microscopic descriptions:</label></legend>
<p><label class="description">- Tumor histology and immunohistochemical studies: </label>
<textarea ID="A08" class="element textarea medium"></textarea>
</p>
<p>
<table border="1">
<col width="40%">
<tr>
<td>
<label class="description">- Histologic type:</label>
</td>
<td>
<select class="element select large" ID="A09">
<option value=""></option>
<option value="Conventional adrenal cortical carcinoma">Conventional adrenal cortical carcinoma</option>
<option value="Oncocytic adrenal cortical carcinoma">Oncocytic adrenal cortical carcinoma</option>
<option value="Myxoid adrenal cortical carcinoma">Myxoid adrenal cortical carcinoma</option>
<option value="Sarcomatoid adrenal cortical carcinoma">Sarcomatoid adrenal cortical carcinoma</option>
<option value="Other histologic subtype not listed (specify):">Other histologic subtype not listed (specify):</option>
<option value="Carcinoma, subtype cannot be determined:">Carcinoma, subtype cannot be determined:</option>
</select>
</td>
</tr>
<tr>
<td>
<label class="description">- <a href=".\cap\Cancer-Protocols-2021-11-Update\Adrenal_4.2.1.0.REL_CAPCP.pdf#page=9" target="_blank">Histologic grade</a>:</label>
</td>
<td valign="top">
<select class="element select large" ID="A10">
<option value=""></option>
<option value="G1: Low grade; mitotic rate < or = 20/10 mm2 (specify: )">G1: Low grade; mitotic rate < or = 20/10 mm2 (specify: )</option>
<option value="G2: High grade; mitotic rate > 20/10 mm2 (specify: )">G2: High grade; mitotic rate > 20/10 mm2 (specify: )</option>
<option value="GX: Cannot be assessed">GX: Cannot be assessed</option>
</select>
</td>
</tr>
<tr>
<td>
<label class="description"> - <a href=".\cap\Cancer-Protocols-2021-11-Update\Adrenal_4.2.1.0.REL_CAPCP.pdf#page=12" target="_blank">Lymphatic and/on vascular invasion</a>: </label>
</td>
<td>
<select class="element select large" ID="A12">
<option value=""></option>
<option value="Not identified">Not identified</option>
<option value="Large vessel invasion, renal vein (including when identified clinically)">Large vessel invasion, renal vein (including when identified clinically)</option>
<option value="Large vessel invasion, vena cava (including when identified clinically) ">Large vessel invasion, vena cava (including when identified clinically)</option>
<option value="Large vessel invasion, not otherwise specified ">Large vessel invasion, not otherwise specified</option>
<option value="Microscopic angioinvasion">Microscopic angioinvasion</option>
<option value="Cannot be determined">Cannot be determined</option>
</select>
</td>
</tr>
<tr>
<td>
<label > + Perineural invasion: </label>
</td>
<td>
<select class="element select large" ID="A13">
<option value=""></option>
<option value="Not identified">Not identified</option>
<option value="Present">Present</option>
<option value="Cannot be determined">Cannot be determined</option>
</select>
</td>
</tr>
<tr>
<td>
<label >+ Necrosis:</label>
</td>
<td>
<select class="element select large" ID="A11">
<option value=""></option>
<option value="Not idenfied">Not idenfied</option>
<option value="Present, extent (%):">Present, extent (%):</option>
<option value="Cannot be assessed">Cannot be assessed</option>
</select>
</td>
<tr>
<td valign="top">
<label class="description">- Tumor extension:</label>
</td>
<td>
<input class="element checkbox" type="checkbox" id="A14" value=" - Not applicable"><label class="choice">Not applicable</label>
<input class="element checkbox" type="checkbox" id="A15" value=" - Confined to adrenal cortex without invasion into or through the adrenal capsule (if present)"><label class="choice">Confined to adrenal cortex without invasion into or through the adrenal capsule (if present)</label>
<input class="element checkbox" type="checkbox" id="A16" value=" - Invades into or through the adrenal capsule, with no peri-adrenal adipose tissue invasion"><label class="choice">Invades into or through the adrenal capsule, with no peri-adrenal adipose tissue invasion</label>
<input class="element checkbox" type="checkbox" id="A17" value=" - Kidney"><label class="choice">Kidney</label>
<input class="element checkbox" type="checkbox" id="A18" value=" - Pancreas"><label class="choice">Pancreas</label>
<input class="element checkbox" type="checkbox" id="A19" value=" - Liver"><label class="choice">Liver</label>
<input class="element checkbox" type="checkbox" id="A55" value=" - Spleen"><label class="choice">Spleen</label>
<input class="element checkbox" type="checkbox" id="A56" value=" - Diaphragm"><label class="choice" >Diaphragm</label>
<input class="element checkbox" type="checkbox" id="A57" value=" - Stomach"><label class="choice">Stomach</label>
<input class="element checkbox" type="checkbox" id="A58" value=" - Peri-adrenal adipose tissue"><label class="choice">Peri-adrenal adipose tissue</label>
<input class="element checkbox" type="checkbox" id="A59" value=" - Large blood vessels"><label class="choice">Large blood vessels</label>
<input class="element checkbox" type="checkbox" id="A60" value=" - Other adjacent organs and structures (specify):"><label class="choice">Other adjacent organs and structures (specify):</label>
<input class="element checkbox" type="checkbox" id="A61" value=" - Cannot be determined: "><label class="choice">Cannot be determined: </label>
</td>
</tr>
<tr>
<td valign="top">
<label > + <a href=".\cap\Cancer-Protocols-2021-11-Update\Adrenal_4.2.1.0.REL_CAPCP.pdf#page=8" target="_blank">Functional status</a>:</label>
</td>
<td>
<input class="element checkbox" type="checkbox" id="A20" value=" - Urinary 17-ketosteroids increased (10 mg/g creatinine/24 hours)"><label class="choice">Urinary 17-ketosteroids increased (10 mg/g cr/24 hours)</label>
<input class="element checkbox" type="checkbox" id="A21" value=" - Cushing syndrome"><label class="choice">Cushing syndrome</label>
<input class="element checkbox" type="checkbox" id="A22" value=" - Conn syndrome"><label class="choice">Conn syndrome</label>
<input class="element checkbox" type="checkbox" id="A23" value=" - Virilization"><label class="choice">Virilization</label>
<input class="element checkbox" type="checkbox" id="A24" value=" - Feminization"><label class="choice">Feminization</label>
<input class="element checkbox" type="checkbox" id="A25" value=" - Weight loss"><label class="choice">Weight loss</label>
<input class="element checkbox" type="checkbox" id="A26" value=" - Other (specify): "><label class="choice">Other (specify): </label>
</td>
</tr>
<tr>
<td valign="top">
<label class="description"> - <a href=".\cap\Cancer-Protocols-2022-12-Update\Endocrine Protocol Folder\Adrenal_4.3.0.0.REL_CAPCP.pdf#page=19" target="_blank">Ancillary studies</a>:</label>
</td>
<td>
<b><input class="element checkbox" type="checkbox" id="A27" value=" Proliferation index Ki-67 (specify):"><label class="choice">- Proliferation index Ki-67 (specify):</label></b>
<input class="element checkbox" type="checkbox" id="A62" value=" SF1/Melan-A/Calretinin/Inhibin/Synaptophysin: "><label class="choice">+ SF1/Melan-A/Calretinin/Inhibin/Synaptophysin</label>
<input class="element checkbox" type="checkbox" id="A63" value=" p53: "><label class="choice">+ p53</label>
<input class="element checkbox" type="checkbox" id="A64" value=" beta-catenin: "><label class="choice">+ beta-catenin</label>
<input class="element checkbox" type="checkbox" id="A28" value=" Reticulin stain (specify type(s) and result(s)):"><label class="choice">+ Reticulin stain (specify type(s) and result(s)):</label>
<input class="element checkbox" type="checkbox" id="A29" value=" Other (specify type and result):"><label class="choice">+ Other (specify type and result):</label>
</td>
</tr>
</table>
</p>
<p>
- Use 22 mm eyepiece at 40x objective, counting 21 fields, approximates original cut-off of 20 mitosis per 50 high power fields for the 20 mm objective in older microscopes.
</p>
<!--
<p>
<label class="description">- Tumor extension:</label>
<input class="element checkbox" type="checkbox" id="A14" value=" - No evidence of primary tumor"><label class="choice">No evidence of primary tumor</label>
<input class="element checkbox" type="checkbox" id="A15" value=" - Tumor confined to adrenal cortex without invasion through tumor capsule"><label class="choice">Tumor confined to adrenal cortex without invasion through tumor capsule</label>
<input class="element checkbox" type="checkbox" id="A16" value=" - Tumor invades into or through the adrenal capsule"><label class="choice">Tumor invades into or through the adrenal capsule</label>
<input class="element checkbox" type="checkbox" id="A17" value=" - Tumor invades into extra-adrenal structures (specify):"><label class="choice" >Tumor invades into extra-adrenal structures (specify):</label>
<input class="element checkbox" type="checkbox" id="A18" value=" - Tumor invades into adjacent organs (specify):"><label class="choice">Tumor invades into adjacent organs (specify):</label>
<input class="element checkbox" type="checkbox" id="A19" value=" - Cannot be assessed"><label class="choice">Cannot be assessed</label>
</p>
-->
</fieldset>
</p>
<p>
<fieldset style="border-color:#e6e6ff;">
<legend><label class="description">Surgical margins of excision specimen:</label></legend>
<p>
<select class="element select medium" ID="A30">
<option value=""></option>
<option value="Cannot be assessed">Cannot be assessed</option>
<option value="Involved by tumor, specify:">Involved by tumor, specify:</option>
<option value="Uninvolved by tumor, specify location and distance (mm):">Uninvolved by tumor, specify location and distance (mm):</option>
<option value="Not applicable">Not applicable</option>
</select>
</p>
<br>
</fieldset>
</p>
<p>
<fieldset style="border-color:#e6e6ff;">
<legend> <label class="description"> Regional lymph nodes: </label></legend>
<p>
<table border="1">
<col width="75%">
<tr>
<td>
<label class="description">- Number of regional lymph nodes examined:</label>
</td>
<td>
<input type="text" class="element text large" ID="A31" size="15">
</td>
</tr>
<tr>
<td>
<label class="description">- Number of lymph nodes involved (specify locations):</label>
</td>
<td>
<input type="text" class="element text large" ID="A32" size="15">
</td>
</tr>
<tr>
<td>
<label> + Extranodal extension:</label>
</td>
<td>
<select class="element select large" ID="A33">
<option value=""></option>
<option value="Not identified">Not identified</option>
<option value="Present">Present</option>
<option value="Cannot be determined">Cannot be determined</option>
</select>
</td>
</tr>
<tr>
<td>
<label> + Size of largest metastatic deposit (mm), specify site:</label>
</td>
<td>
<input type="text" class="element text large" ID="A34" size="15">
</td>
</tr>
<tr>
<td>
<label> + Size of largest lymph node involved (mm), specify site:</label>
</td>
<td>
<input type="text" class="element text large" ID="A35" size="15">
</td>
</tr>
</table>
</p>
</fieldset>
</p>
<p>
<fieldset style="border-color:#e6e6ff;">
<legend> <label class="description"> Distant Metastasis: </label></legend>
<input class="element checkbox" type="checkbox" id="A48" value=" - Not applicable"><label class="choice" >Not applicable</label>
<input class="element checkbox" type="checkbox" id="A49" value=" - Not identified"><label class="choice" >Not identified</label>
<input class="element checkbox" type="checkbox" id="A50" value=" - Non-regional lymph node(s) (specify):"><label class="choice" >Non-regional lymph node(s) (specify):</label>
<input class="element checkbox" type="checkbox" id="A51" value=" - Lung (specify):"><label class="choice" >Lung (specify):</label>
<input class="element checkbox" type="checkbox" id="A52" value=" - Liver (specify):"><label class="choice" >Liver (specify):</label>
<input class="element checkbox" type="checkbox" id="A53" value=" - Other (specify):"><label class="choice" >Other (specify):</label>
<input class="element checkbox" type="checkbox" id="A54" value=" - Cannot be determined: "><label class="choice" >Cannot be determined: </label>
</fieldset>
</p>
<p>
<fieldset style="border-color:#e6e6ff;">
<legend> <label class="description">Pathologic Stage Classification (AJCC 8e): </label> </legend>
<p>
<table border="1">
<col width="40%">
<tr>
<td valign="top">
<label class="description"> - TNM Descriptors:</label>
</td>
<td>
<input class="element checkbox" type="checkbox" id="A36" value=" m (multiple primary tumors) "><label class="choice">m (multiple primary tumors)</label>
<input class="element checkbox" type="checkbox" id="A37" value=" r (recurrent) "><label class="choice">r (recurrent)</label>
<input class="element checkbox" type="checkbox" id="A38" value=" y (post treatment) "><label class="choice">y (post treatment)</label>
</td>
</tr>
<tr>
<td>
<label class="description"> - <a href=".\cap\Cancer-Protocols-2021-11-Update\Adrenal_4.2.1.0.REL_CAPCP.pdf#page=12" target="_blank">Primary tumor (pT):</a></label>
</td>
<td>
<select class="element select large" ID="A39">
<option value=""></option>
<option value=" - pT not assigned (cannot be determined based on available pathological information)">pT not assigned (cannot be determined based on available pathological information)</option>
<option value=" - pT0: No evidence of primary tumor">pT0: No evidence of primary tumor</option>
<option value=" - pT1: Tumor < or = 5 cm, no extra-adrenal invasion">pT1: Tumor < or = 5 cm, no extra-adrenal invasion</option>
<option value=" - pT2: Tumor > 5 cm, no extra-adrenal invasion">pT2: Tumor > 5 cm, no extra-adrenal invasion</option>
<option value=" - pT3: Tumor of any size with local invasion but not invading adjacent organs">pT3: Tumor of any size with local invasion but not invading adjacent organs</option>
<option value=" - pT4: Tumor of any size that invades adjacent organs (kidney, diaphragm, pancreas, spleen, or liver) or large blood vessels (renal vein or vena cava)">pT4: Tumor of any size that invades adjacent organs (kidney, diaphragm, pancreas, spleen, or liver) or large blood vessels (renal vein or vena cava)</option>
</select>
</td>
</tr>
<tr>
<td>
<label class="description"> - Regional lymph nodes (pN):</label>
</td>
<td>
<select class="element select large" ID="A40">
<option value=""></option>
<option value=" - pN not assigned (no nodes submitted or found)">pN not assigned (no nodes submitted or found)</option>
<option value=" - pN not assigned (cannot be determined based on available pathological information)">pN not assigned (cannot be determined based on available pathological information)</option>
<option value=" - pN0: No regional lymph node metastasis">pN0: No regional lymph node metastasis</option>
<option value=" - pN1: Regional lymph node metastasis">pN1: Regional lymph node metastasis</option>
</select>
</td>
</tr>
<tr>
<td >
<label class="description"> - Distant metastasis (pM):</label>
</td>
<td>
<select class="element select large" ID="A41">
<option value=""></option>
<option value=" - Not applicable - pM cannot be determined from the submitted specimen(s)">Not applicable - pM cannot be determined from the submitted specimen(s)</option>
<option value=" - pM1: Distant metastasis">pM1: Distant metastasis</option>
</select>
</td>
</tr>
<!--
<tr>
<td>
- Specify site(s), if known:
<input type="text" class="element text small" ID="A42" size="35">
</td>
</tr>
-->
</table>
</p>
</fieldset>
</p>
<p>
<fieldset style="border-color:#e6e6ff;">
<legend> <label > + Additional pathologic findings: </label></legend>
<p>
<input class="element checkbox" type="checkbox" id="A43" value=" - Hemorrhage"><label class="choice">Hemorrhage</label>
<input class="element checkbox" type="checkbox" id="A44" value=" - Cystic change"><label class="choice" >Cystic change</label>
<input class="element checkbox" type="checkbox" id="A45" value=" - Calcifications"><label class="choice" >Calcifications</label>
</p>
<p>
- Other (specify):
<input type="text" class = "element text medium" ID="A46" size="35">
</p>
<br>
</fieldset>
</p>
<p>
<label class="description">- Additional notes:</label>
<textarea ID="A47" class = "element textarea medium" style="border-color:Grey;"></textarea>
</p>
<br><br>
<input type="button" name="copyform" value="Check your Report" onclick="updateDescription(this.form)"/>
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<TEXTAREA ID="holdtext" name="holdtext" class="textarea large" style="border-color:coral;"></TEXTAREA>
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<input type="reset" value="Reset Form" name="reset" style="float: right;">
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Last upated on 25-Mar-2023,<br>
based on
<a href="https://www.cap.org/protocols-and-guidelines/cancer-reporting-tools/cancer-protocol-templates" target="_blank">US CAP cancer protocol templates</a>.<br>
Adrenal Gland 4.3.1.0 (Mar 2022).<br>
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Anatomical Pathology Division, Queen Mary Hospital, Hong Kong.
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