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A genomic k-mer counter (and sequence utility) with nice features.

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Meryl

This is 'meryl', a near total rewrite of 'meryl' that appeared in both project kmer and Celera Assembler.

IMPORTANT: Get the latest meryl code from this repo. This is not compatible with old meryl dbs built from canu 1.8 or earlier. The new meryl is significantly faster than the previous version.

meryl dbs are no longer in .mcdat and .mcidx file format. Meryl db is now designed as a DIRECTORY, containing 64 binaries + 64 indexes (128 files).

Dependency

  • gcc 7.4.0 or higher

Installation

Release version: download a stable release version

# Example for Linux-amd64
wget https://github.com/marbl/meryl/releases/download/v1.3/meryl-1.3.Linux-amd64.tar.xz
tar -xJf meryl-1.3.Linux-amd64.tar.xz
export PATH=/path/to/meryl-1.3/build/bin:$PATH

Experimental tip (use git 2.25.1 or higher):

git clone https://github.com/marbl/meryl.git

# build
cd meryl/src
make -j 24
export PATH=/path/to/meryl/*/bin:$PATH

Sequence

This is 'sequence', a utility for working with sequence files.

Evaluate assemblies with k-mers and more

See Merqury.