diff --git a/.gitignore b/.gitignore
index 6a4dae1030..b15ec557cd 100644
--- a/.gitignore
+++ b/.gitignore
@@ -1,2 +1,38 @@
 .DS_Store
 __pycache__
+.AppleDouble
+.LSOverride
+
+__pycache__/
+*.py[cod]
+*$py.class
+
+# C extensions
+*.so
+
+# Distribution / packaging
+.Python
+build/
+develop-eggs/
+dist/
+downloads/
+eggs/
+.eggs/
+parts/
+sdist/
+var/
+wheels/
+pip-wheel-metadata/
+share/python-wheels/
+*.egg-info/
+.installed.cfg
+*.egg
+MANIFEST
+
+*.manifest
+*.spec
+
+pip-log.txt
+pip-delete-this-directory.txt
+
+.tox/
diff --git a/mypy.ini b/mypy.ini
new file mode 100644
index 0000000000..581108ad6f
--- /dev/null
+++ b/mypy.ini
@@ -0,0 +1,9 @@
+[mypy]
+disallow_incomplete_defs = True
+disallow_untyped_defs = True
+
+warn_unused_ignores = True
+warn_unused_configs = True
+warn_redundant_casts = True
+
+ignore_missing_imports = True
diff --git a/pyproject.toml b/pyproject.toml
new file mode 100644
index 0000000000..9b0bc46621
--- /dev/null
+++ b/pyproject.toml
@@ -0,0 +1,10 @@
+[build-system]
+requires = ["setuptools", "wheel"]
+build-backend = "setuptools.build_meta"
+
+[tool.isort]
+profile = "black"
+multi_line_output = 3
+
+[tool.black]
+line-length = 79
diff --git a/setup.cfg b/setup.cfg
new file mode 100644
index 0000000000..954af6382b
--- /dev/null
+++ b/setup.cfg
@@ -0,0 +1,29 @@
+[metadata]
+name = eth1spec
+description = Ethereum specification, provided as a Python package for tooling
+    and testing
+version = 0.1.0
+url = https://github.com/ethereum/eth2.0-specs
+
+[options]
+packages = eth1spec
+package_dir =
+    =src
+
+python_requires = >=3.7
+install_requires =
+    pysha3>=1,<2
+    coincurve>=15,<16
+
+[options.extras_require]
+test =
+    pytest>=6.2,<7
+    pytest-cov>=2.12,<3
+
+lint =
+    isort>=5.8,<6
+    mypy==0.812; implementation_name == "cpython"
+    black==21.5b2; implementation_name == "cpython"
+    flake8>=3.9,<4
+
+# vim: set ft=dosini:
diff --git a/setup.py b/setup.py
new file mode 100644
index 0000000000..938f7a0d3e
--- /dev/null
+++ b/setup.py
@@ -0,0 +1,12 @@
+import pathlib
+
+import setuptools
+
+here = pathlib.Path(__file__).parent.resolve()
+
+long_description = (here / "README.md").read_text(encoding="utf-8")
+
+setuptools.setup(
+    long_description=long_description,
+    long_description_content_type="text/markdown",
+)
diff --git a/spec/requirements.txt b/spec/requirements.txt
deleted file mode 100644
index 3c6cd0d3e0..0000000000
--- a/spec/requirements.txt
+++ /dev/null
@@ -1,2 +0,0 @@
-pysha3==1.0
-coincurve==15.0
diff --git a/spec/crypto.py b/src/eth1spec/crypto.py
similarity index 100%
rename from spec/crypto.py
rename to src/eth1spec/crypto.py
diff --git a/spec/eth_types.py b/src/eth1spec/eth_types.py
similarity index 100%
rename from spec/eth_types.py
rename to src/eth1spec/eth_types.py
diff --git a/spec/evm.py b/src/eth1spec/evm.py
similarity index 100%
rename from spec/evm.py
rename to src/eth1spec/evm.py
diff --git a/spec/main.py b/src/eth1spec/main.py
similarity index 100%
rename from spec/main.py
rename to src/eth1spec/main.py
diff --git a/spec/rlp.py b/src/eth1spec/rlp.py
similarity index 100%
rename from spec/rlp.py
rename to src/eth1spec/rlp.py
diff --git a/spec/spec.py b/src/eth1spec/spec.py
similarity index 100%
rename from spec/spec.py
rename to src/eth1spec/spec.py
diff --git a/spec/trie.py b/src/eth1spec/trie.py
similarity index 100%
rename from spec/trie.py
rename to src/eth1spec/trie.py
diff --git a/tests/__init__.py b/tests/__init__.py
new file mode 100644
index 0000000000..e69de29bb2
diff --git a/tests/fixtures b/tests/fixtures
deleted file mode 160000
index 82f6a5a736..0000000000
--- a/tests/fixtures
+++ /dev/null
@@ -1 +0,0 @@
-Subproject commit 82f6a5a7362e703a64dce303dd0c30f264b8195f
diff --git a/spec/fixtures/genesis/alloc.json b/tests/fixtures/genesis/alloc.json
similarity index 100%
rename from spec/fixtures/genesis/alloc.json
rename to tests/fixtures/genesis/alloc.json
diff --git a/spec/fixtures/genesis/env.json b/tests/fixtures/genesis/env.json
similarity index 100%
rename from spec/fixtures/genesis/env.json
rename to tests/fixtures/genesis/env.json
diff --git a/spec/fixtures/genesis/txs.json b/tests/fixtures/genesis/txs.json
similarity index 100%
rename from spec/fixtures/genesis/txs.json
rename to tests/fixtures/genesis/txs.json
diff --git a/spec/fixtures/sample/alloc.json b/tests/fixtures/sample/alloc.json
similarity index 100%
rename from spec/fixtures/sample/alloc.json
rename to tests/fixtures/sample/alloc.json
diff --git a/spec/fixtures/sample/env.json b/tests/fixtures/sample/env.json
similarity index 100%
rename from spec/fixtures/sample/env.json
rename to tests/fixtures/sample/env.json
diff --git a/spec/fixtures/sample/txs.json b/tests/fixtures/sample/txs.json
similarity index 100%
rename from spec/fixtures/sample/txs.json
rename to tests/fixtures/sample/txs.json
diff --git a/tests/test_spec.py b/tests/test_spec.py
new file mode 100644
index 0000000000..0f6816f185
--- /dev/null
+++ b/tests/test_spec.py
@@ -0,0 +1,18 @@
+from eth1spec.spec import Account, State, get_account
+
+
+def test_get_account():
+    account = Account(
+        nonce=0,
+        balance=1,
+        code_hash=b"bbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbb",
+    )
+
+    state = State()
+    state[b"aaaaaaaaaaaaaaaaaaaa"] = account
+
+    actual = get_account(state, b"aaaaaaaaaaaaaaaaaaaa")
+
+    assert actual.nonce == 0
+    assert actual.balance == 1
+    assert actual.code_hash == b"yyyyyyyyyyyyyyyyyyyyyyyyyyyyyyyy"
diff --git a/tox.ini b/tox.ini
new file mode 100644
index 0000000000..50407f2d0c
--- /dev/null
+++ b/tox.ini
@@ -0,0 +1,22 @@
+[tox]
+envlist = py3,pypy3
+
+[testenv]
+extras =
+    test
+    lint
+commands =
+    isort src tests setup.py --check --diff
+    black src tests setup.py --check --diff
+    pyflakes src tests setup.py
+    mypy src tests setup.py
+    pytest
+
+[testenv:pypy3]
+extras =
+    test
+    lint
+commands =
+    isort src tests setup.py --check --diff
+    pyflakes src tests setup.py
+    pytest