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Dear Xiaowei, I was looking at the columns in my rvtest output but somehow the AF (I guess standing for allele frequency) does not match with the report in the columns N_REF, N_HET and N_ALT.
For example
N_REF=1200; N_HET=125; N_ALT=0; reports in the AF column 0.305
How could this be? from my manual calculation Freq_REF=0.953 and Freq_Alt=1-0.953
Also, the reported HWE Pval is 0.11, how could this be?
I have done the excercise for 17 SNPs (header of one of my files and none of the AF was similar to the reported one caro_rvtest.xlsx
The text was updated successfully, but these errors were encountered:
Dear Xiaowei, I was looking at the columns in my rvtest output but somehow the AF (I guess standing for allele frequency) does not match with the report in the columns N_REF, N_HET and N_ALT.
For example
N_REF=1200; N_HET=125; N_ALT=0; reports in the AF column 0.305
How could this be? from my manual calculation Freq_REF=0.953 and Freq_Alt=1-0.953
Also, the reported HWE Pval is 0.11, how could this be?
I have done the excercise for 17 SNPs (header of one of my files and none of the AF was similar to the reported one
caro_rvtest.xlsx
The text was updated successfully, but these errors were encountered: