Beat determines editing efficiency after subtracting the background noise without the need to normalize to control samples. It finds the noise and filters the outliers from the noise using the Median Absolute Deviation (MAD) method
To access the online tool, please follow this link: https://hanlab.cc/beat/
Please cite our paper if you use BEAT for your work: Xu L, Liu Y, Han R. (2019) BEAT: A python program to quantify base editing from Sanger sequencing. CRISPR J doi: 10.1089/crispr.2019.0017.