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Jupyter Notebook 14 4 Updated Aug 7, 2024

deep learning-inspired explainable sequence model for transcription initiation

Python 88 7 Updated Sep 27, 2024

Code for the data processing and analyses present on the manuscript: "Cellular energy regulates mRNA translation and degradation in a codon-specific manner".

Jupyter Notebook 2 Updated Feb 22, 2023
Jupyter Notebook 482 101 Updated Dec 17, 2023

Draw RNA secondary structures in python.

Jupyter Notebook 40 14 Updated Sep 3, 2024

Neural network regression model of translation elongation rate, with DP algorithm to optimize fast coding sequences under model

Python 8 7 Updated May 3, 2018

Predicting ribosome stalling using ROSE.

Python 4 1 Updated Jun 23, 2017
PureBasic 13 5 Updated Mar 6, 2024

CodonTransformer: The ultimate tool for codon optimization, optimizing DNA sequences for heterologous protein expression across 164 species.

Python 93 3 Updated Sep 26, 2024

Repository for MolFormer

Jupyter Notebook 258 41 Updated Oct 16, 2023

bpRNA: Large-scale Annotation and Analysis of RNA Secondary Structure

Perl 43 11 Updated Nov 23, 2023

Code repository of "Deep generative design of RNA family sequences"

Jupyter Notebook 27 7 Updated Jul 17, 2024
Jupyter Notebook 65 14 Updated Oct 9, 2024

Evolutionary Scale Modeling (esm): Pretrained language models for proteins

Python 3,194 634 Updated Feb 7, 2024

Efficient evolution from protein language models

Python 169 42 Updated Aug 26, 2023

Computationally Restoring the Potency of a Clinical Antibody

Python 16 1 Updated Mar 1, 2024

Protein language model trained on coding DNA

Python 37 10 Updated Mar 2, 2024

Open source code for AlphaFold.

Python 19 10 Updated Jul 2, 2023

This package contains deep learning models and related scripts for RoseTTAFold

Python 2,007 438 Updated Feb 15, 2024
Python 166 39 Updated Oct 3, 2024

gReLU is a python library to train, interpret, and apply deep learning models to DNA sequences.

Python 210 21 Updated Oct 16, 2024
Jupyter Notebook 8 2 Updated Nov 6, 2023

CodonBert: a BERT-based architecture tailored for codon optimization using the cross-attention mechanism.

Python 17 1 Updated Sep 12, 2024

🧬 Generative modeling of regulatory DNA sequences with diffusion probabilistic models 💨

Python 361 51 Updated Oct 15, 2024

Rational Oligonucleotide design Calculated with Kinetic parameter for Enhanced in vitro Transcription

Python 2 Updated Jun 26, 2024

Genome-wide Efficient Mixed Model Association

C++ 331 125 Updated May 3, 2024

Various algorithms for analysing genomics data

Java 189 59 Updated Oct 16, 2024

Module and script to remove contamination in assembled genomes before submission to ncbi

Python 14 Updated Apr 30, 2018

Repository for mRNA Paper and CodonBERT publication.

Python 107 16 Updated Jun 12, 2024
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