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Code for manuscript "A simplified MyProstateScore2.0 for high-grade prostate cancer"

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Simplified MyProstateScore2.0 (sMPS2)

Code to reproduce results and figures in manuscript:

Tiffany M. Tang*, Yuping Zhang*, Ana M. Kenney, Cassie Xie, Lanbo Xiao, Javed Siddiqui, Sudhir Srivastava, Martin G. Sanda, John T. Wei, Ziding Feng, Jeffrey J. Tosoian, Yingye Zheng, Arul M. Chinnaiyan†, and Bin Yu†; for the EDRN-PCA3 Study Group. "A simplified MyProstateScore2.0 for high-grade prostate cancer". Cancer Biomarkers. 2025;42(1). doi:10.1177/18758592241308755

Accompanying supplementary PCS documentation: https://yu-group.github.io/sMPS2/

In this work, we developed and rigorously stress-tested a novel non-invasive biomarker test, the simplified MyProstateScore2.0 (sMPS2), for accurate and early screening of clinically-significant prostate cancer.

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To cite sMPS2, please use:

@article{tang2025simplified,
  author = {Tiffany M Tang and Yuping Zhang and Ana M Kenney and Cassie Xie and Lanbo Xiao and Javed Siddiqui and Sudhir Srivastava and Martin G Sanda and John T Wei and Ziding Feng and Jeffrey J Tosoian and Yingye Zheng and Arul M Chinnaiyan and Bin Yu},
  title ={A simplified MyProstateScore2.0 for high-grade prostate cancer},
  journal = {Cancer Biomarkers},
  volume = {42},
  number = {1},
  pages = {18758592241308755},
  year = {2025},
  doi = {10.1177/18758592241308755},
  note = {PMID: 40109218},
  URL = {https://doi.org/10.1177/18758592241308755}
}

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