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Update README.md
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a-xavier authored Nov 9, 2020
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Please refer to the [WIKI](https://github.com/a-xavier/tapes/wiki) for more information on all TAPES functions.
See [HERE for installation and dependencies resolutions](https://github.com/a-xavier/tapes/wiki/Installation-and-Dependencies).

## Warning
The command ```perl annotate_variation.pl -buildver hg19 -downdb -webfrom annovar avdblist ./``` does not seem to download the list of databases available for ANNOVAR anymore (this might be temporary).
If this happens, please download:
[https://github.com/a-xavier/tapes/files/5507866/hg19_avdblist.txt](https://github.com/a-xavier/tapes/files/5507866/hg19_avdblist.txt)
and
[https://github.com/a-xavier/tapes/files/5507867/hg38_avdblist.txt](https://github.com/a-xavier/tapes/files/5507867/hg38_avdblist.txt)
and place them in your ANNOVAR folder (where ```annotate_variation.pl``` is located).


## TAPES purpose
TAPES is an open-source tool written in __python3__ designed to __predict pathogenicity__ of variants in __exome studies__.
It is especially designed for small scalle exome studies (from dozens to a few hundreds) sharing a common trait/phenotype.
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