Skip to content

Commit

Permalink
Merge pull request #63 from bcgsc/warrenlr-patch-2
Browse files Browse the repository at this point in the history
Update README.md
  • Loading branch information
warrenlr authored Apr 26, 2024
2 parents c871bbc + 659e739 commit 9496cd4
Showing 1 changed file with 1 addition and 2 deletions.
3 changes: 1 addition & 2 deletions README.md
Original file line number Diff line number Diff line change
Expand Up @@ -39,8 +39,7 @@ ntEdit is a fast and scalable genomics application for polishing genome sequence
It simplifies polishing, variant detection and "haploidization" of gene and genome sequences with its re-usable Bloom filter design.
Although it was originally designed as a general-purpose polishing tool, initally aimed at improving genome sequences by fixing base mismatches and frame shift errors with the help of more base-accurate short sequencing reads, ntEdit can also be used for polishing with long reads and to "finish" genome sequence assembly projects (refer to <a href="https://github.com/bcgsc/goldPolish" target="_blank">GoldPolish</a> and the <a href="https://github.com/bcgsc/ntedit_sealer_protocol" target="_blank">ntedit+sealer genome assembly finishing protocol</a>, respectively).

We anticipate that ntEdit will find further applications in the rapid mapping of single nucleotide variants, as demonstrated below with the genome of SARS-CoV-2, the highly transmissible pathogenic coronavirus, and etiological agent of COVID-19.

We anticipate that ntEdit will find further applications in the rapid mapping of single nucleotide variants, as demonstrated below with the genome of SARS-CoV-2, the highly transmissible pathogenic coronavirus, and etiological agent of COVID-19. Additionally, for researchers delving into the intricate roots of genetic lineages within large cohort data, we encourage the utilization of <a href="https://github.com/bcgsc/ntroot" target="_blank">ntRoot, an ancestry prediction framework</a> built upon the ntEdit engine. It offers a comprehensive analysis of genetic heritage, employing sequence alignment-free algorithms to unveil ancestral connections and provide insights into genetic ancestry within diverse populations.

```diff
! NOTE: In v1.3.1 onwards, the parameter k is automatically detected from supplied Bloom filters
Expand Down

0 comments on commit 9496cd4

Please sign in to comment.