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Update faq.rst
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skoren authored Oct 13, 2017
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Expand Up @@ -85,7 +85,7 @@ What parameters should I use for my reads?
over-estimate of true error, inflating runtime. For recent large genomes (>1gbp) with more
than 30x coverage, we've used ``'corMhapOptions=--threshold 0.8 --num-hashes
512 --ordered-sketch-size 1000 --ordered-kmer-size 14'``. This is not needed for below 30x
coverage.
coverage. You can also try the ``overlapper=mhap utgReAlign=true`` option which is much faster but may produce less contiguous assemblies.


My assembly continuity is not good, how can I improve it?
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For low coverage:

- For less than 30X coverage, increase the alllowed difference in overlaps by a couple of percent (from 4.5% to 6.5%
(or more) with ``correctedErrorRate=0.075`` for PacBio and from 14.4% to 16% (or more) with ``correctedErrorRate=0.16`` for Nanopore), to adjust for inferior read correction. Canu
- For less than 30X coverage, increase the alllowed difference in overlaps by a few percent (from 4.5% to 8.5%
(or more) with ``correctedErrorRate=0.105`` for PacBio and from 14.4% to 16% (or more) with ``correctedErrorRate=0.16`` for Nanopore), to adjust for inferior read correction. Canu
will automatically reduce ``corMinCoverage`` to zero to correct as many reads as possible.

For high coverage:
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