Developmental hematopoietic stem cell fate decisions explain clonal dynamics over lifetime

Citation

If you use FMCs_for_HSCs in your research, please cite the bioRxiv preprint avaible here:

J Kreger, D Shibata, AL MacLean (2023). Developmental hematopoietic stem cell fate decisions explain clonal dynamics over lifetime.

The bioRxiv version is available here.

Overview

This repository contains code used in the analysis of clonal dynamics of hematopoietic stem cells. The code is written in Julia (tested on versions 1.8.1) and is presented in a Jupyter notebook (Developmental_hematopoietic_stem_cell_fate_decisions_explain_clonal_dynamics_over_lifetime.ipynb).

Data used in the analysis is included in the file (?.xlsx). This data is from...

Requirements

• Julia (version 1.8.1) or newer
• Jupyter notebook

Package requirements

• Statistics.jl
• LinearAlgebra.jl
• DataStructures.jl
• StatsBase.jl
• StatsPlots.jl
• Distributions.jl
• LsqFit.jl
• Random.jl
• ColorSchemes.jl
• Plots.jl; pyplot()
• DelimitedFiles.jl

Project contents

• README.md : this file with information about the repository and paper
• Developmental_hematopoietic_stem_cell_fate_decisions_explain_clonal_dynamics_over_lifetime.ipynb : Jupyter notebook containing code blocks for all simulations and figures in the paper.
• ?.xlsx : data used in the analysis, see...

Acknowledgments

We would like to thank... Figures... were created with BioRender.

Contributors