modified: 0abstractbump.md

	modified:   a0004z.md
	modified:   a0008z.md
	modified:   a0011z.md
	modified:   a0016z.md
	modified:   a0018z.md
	modified:   a0026z.md
	modified:   a0041z.md
	modified:   a0053z.md
	modified:   a0132z.md
	modified:   a0221z.md
	modified:   a0277z.md
	modified:   a0598z.md
	modified:   a0644z.md
	modified:   b0003y.md
	modified:   b0042y.md
	modified:   b0047y.md
	modified:   b0068y.md
	modified:   b0069y.md
	modified:   b0072y.md
	modified:   b0074y.md
	modified:   b0075y.md
	modified:   b0080y.md
	modified:   b0091y.md
	modified:   b0097y.md
	modified:   b0101y ctpr.txt
	modified:   b0103y ctpr.txt
	modified:   b0104y.md
	modified:   b0106y ctpr.txt
	modified:   b0109y ctpr.txt
	modified:   b0110y ctpr.txt
	modified:   b0114y.md
	modified:   b0116y.md
	modified:   b0122y  ctpr.txt
	modified:   b0124y ctpr.txt
	modified:   b0127y ctpr.txt
	modified:   b0130y.md
	modified:   b0132y ctpr.txt
	modified:   b0145y ctpr.txt
	modified:   b0146y ctpr.txt
	modified:   b0151y.md
	modified:   b0155y ctpr.txt
	modified:   b0165y ctpr.txt
	modified:   b0178y ctpr.txt
	modified:   b0183y ctpr.txt
	modified:   b0195y ctpr.txt
	modified:   b0197y ctpr.txt
	modified:   b0209y ctpr.txt
	modified:   b0230y ctpr.txt
	modified:   b0251y (audio) ctpr.txt
	modified:   b0252y.md
	modified:   b0267y ctpr.txt
	modified:   b0268y ctpr.txt
	modified:   b0271y ctpr.txt
	modified:   b0272y.md
	modified:   b0276y.md
	modified:   b0302y.md
	modified:   b0305y.md
	modified:   b0308y.md
	modified:   b0309y.md
	modified:   b0310y.md
	modified:   b0311y.md
	modified:   b0313y.md
	modified:   b0314y.md
	modified:   b0324y.md
	modified:   b0328y.md
	modified:   map.napot.md
	modified:   nlp1
	modified:   nlp2
	modified:   nlp3

0abstractbump.md

@@ -1,23 +1,3 @@
 This note is intended to be deleted regularly below the 3rd line. Essentially it's a copy/paste pad for working across notes. An external short term memory aid.
 If you are new here. 1. Check the Readme.md for updates. 2. Check the Wiki for contents.
-This is the 3rd line..
-
-# Morphology
-
-# On LTP Memory & Dendritic Morphology
-
-My updated conjecture is that long term memories are not just from synaptic connections but essentially they are from the morphology of the cell itself, specifically the morphology of the dendrite, because that determines what signal patterns the dendrite (or the cell) responds, how great the magnitude cellular response is, and what types of variations in the signal the cell might create at the exit terminal of individual synapses.
-
-When a cell gets part of a pattern it updates its synapses, might cause a tiny phase change in its tonic oscillation timing that the rest of the oscillating cell assembly to notice. I am looking at Olfactory bulb research to understand how a cell might instantly update it's sensory input with a partial pattern. Do Potassium receptors get upregulated or down regulated? There was a study on Umami (search my notes, currently in note a0272z) that compared that suggested "taste detection of glutamate (and presumably other amino acids) seems primarily to involve G protein–coupled receptors."
-
-# "Dopaminergic neurons dynamically update sensory values during navigation"
-"Notably, odors alone induced value- and dopamine-dependent changes in the activity of mushroom body output neurons, which store the current value of odors, as well as the behavior of flies steering in a virtual environment."
-doi: https://doi.org/10.1101/2022.08.17.504092
-
-# "The olfactory bulb carries out concentration invariance calculations by itself and does it very quickly."
-
-
-Astrocytes
-# "Centripetal integration of past events by hippocampal astrocytes"
-"astrocytes (are) computational units of the brain that slowly and conditionally integrate information about the past."
-doi: https://doi.org/10.1101/2022.08.16.504030
+This is the 3rd line..

a0004z.md

@@ -18,4 +18,7 @@ It is thought that brainwaves are gaussian like pink noise, in sync, but essenti
 
 The tonic oscillatory noise I argue provides for the ground of being, awareness, raw experiential conscious expectation that new information from our senses and the content or patterns inside our mind arise from.
 
-In that sense Stable Diffusion is a better analogy for how our minds create representations of reality, how our minds are capable of hallucinations, dreams, out of body experiences, drug induced altered states of mind, spiritual experiences, visions, and experiences that we might call episodes of in the zone creativity, inspiration, and or imagination.
+In that sense Stable Diffusion is a better analogy for how our minds create representations of reality, how our minds are capable of hallucinations, dreams, out of body experiences, drug induced altered states of mind, spiritual experiences, visions, and experiences that we might call episodes of in the zone creativity, inspiration, and or imagination.
+
+Rephrasing:
+As a signal train moves along a neural pathway goes from being a train of action potential spikes & chemical phase changes in temporal spatial patterns across the brain it's signal power is dissipated across the oscillating neural cell assemblies, absorbed into the tonic firing rate, while altering the tonic firing rate, but the tonic oscillation has been described as a noise pattern. In essence the high phasic waves are rare and in the context of information theory that means their information content is high, the tonic waves are extremely common place and so their information value is extremely low, but there is an analogy to Stable Diffusion AI because over time that high information signal pattern is being noised, with each iterative oscillation that turns what was a high phasic firing pattern into a tonic oscillation again. It is analogous to adding noise to an imagine over time, perhaps the high information pattern oscillates enough times to change the growth pattern of synapses (and perhaps it does not, such as in the case of seeing an illusion) and so the tonic brainwave oscillation remains trained & ready to conjure any sort of mental imagine based on the spike trains that push high phasic burstlets into it's oscillating matrix.

a0008z.md

@@ -86,6 +86,8 @@ Neurons are information programs that transmit a phase change that represents th
 
 In a valid sense the neuron is reporting it's learned morphology including it's synaptic connection configuration to the rest of it's oscillatory group. The learned morphology is going to affect the equation at the topic, the rate of change in X - the rate in change in Y. If a neuron grows a lot of new receptors, sodium or potassium receptors, that changes the core equation, the rates of change in X & Y, so a neuron can grow more sensitive or less sensitive with more receptors depending on the type, the location, and the types of incoming signals the neuron is receptive to, because of morphological changes to it's leaky membrane that might dissipate charge increments coming in with certain patterns, or the cell might act on charge increments with certain other patterns based on it's morphological structure.
 
+
+
 A new protein, such as what happens during LTP changes the cells morphology, the cell has now grown, so it's response is altered slightly.
 
 # In 2014 I called this the Neurons are transmitting their shapes theory.

a0011z.md

@@ -81,6 +81,12 @@ The soma burst is just one type of threshold mechanism, receptors also have thre
 
 NAPOT Neural Array Projection Oscillatory Tomography includes communication with Astrocytes, Oligodendrocytes, T-Cells, Microglia, and basically any type of cell. NAPOT interfaces with all cells via COT Cellular Oscillating Tomography, because all cells exchange signals, and have receptors, membranes, and other structures to receive signals & detect information from temporal cascades of coincident activations.
 
+Astrocytes
+# "Centripetal integration of past events by hippocampal astrocytes"
+"astrocytes (are) computational units of the brain that slowly and conditionally integrate information about the past."
+(centripetal integration implies that astrocytes can sort of pool information (or summarize input) like the action potential of a neuron, albiet at a slower rate)
+doi: https://doi.org/10.1101/2022.08.16.504030
+
 Astrocytes can compute paper https://www.biorxiv.org/content/10.1101/2021.10.20.465192v3
 
 # "Variation in voltages (or a lack of it) within an astrocyte network can also explain the" Variations in voltages are phase changes.
@@ -100,21 +106,61 @@ https://www.discovermagazine.com/mind/research-reveals-surprising-conversations-
 
 Most of the worlds biologists and neuroscientists do not realize what is perfectly obvious, which is that ordinary cells are capable of hebbian learning, receptors are sensors, as receptors can grow to represent a memory as a physical sensor configuration that is responsive to certain criteria
 
-/////////////////////////////////////////////////
+////////////////////////////////////////////////////////////////
+
+# Mechanoreceptors sensors in skin for touch
 
 # Recap: Cellular Oscillation Tomography, or Cell Tomography for short.
 
 All cells oscillate, they are dissipative systems, they have frequency patterns, they are functionally vortices.
 
 Receptors enable a cell to detect patterns, the more receptors that are affected, the greater the cell's reaction, receptors have thresholds for activation, but cells can also detect when multiple receptors have been triggered via inner threshold mechanisms that span between receptors.
 
-Sometimes Potassium channel receptors are bound by Ankyrin Repeats and that makes the receptor surface area larger so the cell becomes sensitive to mechano-scale waves, in other words now the cell can react to touch.
+Sometimes Potassium channel receptors are bound by Ankyrin Repeats and that makes the receptor surface area larger so the cell becomes sensitive to mechano-scale waves, in other words now the cell can react to touch. It becomes one type of mechanoreceptor.
 
 In a sense that Ankyrin Repeat is allowing the cell to detect the coincident features of a mechanical scale wave (acoustic scale wave or sound vibration scale wave)
 
 So any surface area could be part of a sensor, and if the sensor has different thresholds for activating different functions its a coincidence detector, the shape, topology, morphology, and physical configuration of the sensor determine what types of signals it is capable of responding to, and what types of signals it ignores, so the shape of the sensor can act as a learned memory, and this is why the learned receptor configuration on any cell in any organism is effectively a long term memory that exists to react or activate a function (a cell behavior) upon activation.
 
-///////////////////////////////////////////////////
+# "Ankyrin Is An Intracellular Tether for TMC Mechanotransduction Channels"
+"Here, we identify UNC-44/ankyrin as an essential component of the TMC-1 mechanotransduction channel complex in the sensory cilia of Caenorhabditis elegans mechanoreceptor neurons. Ankyrin binds indirectly to TMC-1 via evolutionarily conserved CIB proteins, which are required for TMC-1-mediated mechanosensation in C. elegans OLQ neurons and body wall muscles. Mechanosensory activity conferred by ectopically expressed TMCs in mechanoinsensitive neurons depends on both ankyrin and CIB proteins, indicating that the ankyrin-CIB subcomplex is required for TMC mechanosensitivity. Our work indicates that ankyrin is a long-sought intracellular tether that transmits force to TMC mechanotransduction channels."
+https://pubmed.ncbi.nlm.nih.gov/32325031/
+
+////////////////////////////////////////////////////////////////
+
+# Thermoreceptors
+"A thermoreceptor is a non-specialised sense receptor, or more accurately the receptive portion of a sensory neuron, that codes absolute and relative changes in temperature, primarily within the innocuous range. In the mammalian peripheral nervous system, warmth receptors are thought to be unmyelinated C-fibres (low conduction velocity), while those responding to cold have both C-fibers and thinly myelinated A delta fibers (faster conduction velocity).[1] The adequate stimulus for a warm receptor is warming, which results in an increase in their action potential discharge rate. Cooling results in a decrease in warm receptor discharge rate. For cold receptors their firing rate increases during cooling and decreases during warming. Some cold receptors also respond with a brief action potential discharge to high temperatures, i.e. typically above 45 °C, and this is known as a paradoxical response to heat. The mechanism responsible for this behavior has not been determined."
+https://en.wikipedia.org/wiki/Thermoreceptor
+
+
+////////////////////////////////////////////////////////////////
+
+# Morphology
+
+# On LTP Memory & Dendritic Morphology
+
+My updated conjecture is that long term memories are not just from synaptic connections but essentially they are from the morphology of the cell itself, specifically the morphology of the dendrite, because that determines what signal patterns the dendrite (or the cell) responds, how great the magnitude cellular response is, and what types of variations in the signal the cell might create at the exit terminal of individual synapses.
+
+When a cell gets part of a pattern it updates its synapses, might cause a tiny phase change in its tonic oscillation timing that the rest of the oscillating cell assembly to notice. I am looking at Olfactory bulb research to understand how a cell might instantly update it's sensory input with a partial pattern. Do Potassium receptors get upregulated or down regulated? There was a study on Umami (search my notes, currently in note a0272z) that compared that suggested "taste detection of glutamate (and presumably other amino acids) seems primarily to involve G protein–coupled receptors."
+
+# "Dopaminergic neurons dynamically update sensory values during navigation"
+"Notably, odors alone induced value- and dopamine-dependent changes in the activity of mushroom body output neurons, which store the current value of odors, as well as the behavior of flies steering in a virtual environment."
+doi: https://doi.org/10.1101/2022.08.17.504092
+
+# "The olfactory bulb carries out concentration invariance calculations by itself and does it very quickly."
+" The computations for concentration invariance are most likely carried out within the olfactory bulb itself and they are carried out quickly."
+https://www.biorxiv.org/content/10.1101/2022.08.17.504274v1
+
+# The Olfactory System
+"Transduction of olfactory information occurs when odorant molecules contact the dendrites of olfactory-receptor neurons (ORNs). These neurons reside in the olfactory epithelium, a specialized region of the dorsal nasal cavity. ORN axons project through the lamina propria underlying the olfactory epithelium, and into the glomerular layer of the olfactory bulb. This projection forms the olfactory nerve, or cranial nerve I. Within glomeruli, ORN axons synapse onto the apical dendrites of mitral and tufted cells, which are the output neurons of the olfactory bulb. In turn, axons from these cells project to the primary olfactory cortex, through the lateral olfactory tract. The primary olfactory cortex comprises several brain regions, including the anterior olfactory nucleus, the piriform cortex, parts of the amygdala, and the entorhinal cortex.
+https://link.springer.com/chapter/10.1007/978-1-59259-371-2_27
+
+# "Olfactory memory representations are stored in the anterior olfactory nucleus"
+"The anterior olfactory nucleus (AON) (...) detects the coincidence of these inputs, generating patterns of activity reflective of episodic odour engrams."
+"Previously, we demonstrated that odour perception can be altered by AON activity modulation. We also found that the AON receives dense, topographically organised projections from the hippocampus, a structure highly implicated in navigation and episodic memory"
+https://www.nature.com/articles/s41467-020-15032-2
+
+////////////////////////////////////////////////////////////////
 
 Cellular Oscillation Tomography means every cell can encode memory (LTP) in the information configuration of its receptors, recognize patterns via Hebbian learning, and execute functions computed by evolution, saved in protein configurations. https://github.com/v5ma/selfawarenetworks/blob/main/a0011z.md
 

a0016z.md

@@ -1,7 +1,15 @@
 a0016z
+
+(The notes that mention Neo Mind Cycle are originally from the era between 2011-2015)
+
 (cortex)
+
 The full Neo Mind Cycle program included nutrition & supplements, not just brain stimulation and neurofeedback, this was a similar to try a little of everything approach in the book about D-ribose "From Fatigued to Fantastic Paperback" by Jacob Teitelbaum M.D. (Author)
 
 Neo Mind refers to the Neo Cortex, aka the New Rind, aka the giant thing that makes human brains distinct and new from other species
 Neurofeedback the way I do it isn't just feedback, it's a feedback loop. or cycle,
 hence Neo Mind Cycle: Optimizing your brain is just part of a healthy lifestyle.
+
+# "Self-modulation of motor cortex activity after stroke: a randomized controlled trial"
+Interesting mri / eeg neurofeedback article for folks who had a stroke 
+https://academic.oup.com/brain/advance-article/doi/10.1093/brain/awac239/6663819

a0018z.md

@@ -51,6 +51,8 @@ https://www.nature.com/articles/s41467-022-31072-2?fbclid=IwAR2cCdaa_FisM7C9CODf
 
 # Hippocampus
 
+I regard the hippocampus as like cortical column #1, it is a unique structure but in essence it embodies the key characteristics of an oscillating cortical column. The hippocampal-entorhinal loop might have a central role in your cognition, but essentially all of your oscillating cell assemblies are playing a role in sentient self awareness.
+
 # "A Cellular Positioning System to Probe Morphological Heterogeneity Among Mouse CA3 Hippocampal Pyramidal Neurons"
 "Some heterogeneous structural and functional features of these neurons vary in a topographically patterned way and are essential for proper hippocampal function. For example, in CA3, place field size, pattern completion, and sharp wave initiation are all arranged topographically3,5–9. Specific locations within CA3 are recruited during both spatial10–14 and non-spatial learning and memory15. Focal lesions within specific CA3 subfields can lead to disrupted fear memory16 or spatial processing17. Chronic social stress also perturbs CA3 dendritic morphology and concomitantly impairs spatial learning and memory, likely in a topographically patterned way18"
 "No study to date (to our knowledge) has studied dendritic morphology along all three axes simultaneously. We believe this is due to a methodological gap. We sought to fill this gap by establishing proof of principle in collecting and analyzing detailed topographic and 

a0026z.md

@@ -109,7 +109,7 @@ As I have been writing this book I have all along been looking inside my mind wa
 
 understanding that my mind is a phase field, with a holographic soliton multi frequence range (solitons in fields of electric(ion movement), magnetic(ion), mechanical (acoustic), chemical(waves), and thermo (heat)
 
- pattern being emitted in the synaptic cleft as a phase change in phase space that knocks another oscillator contributing to a phase pattern that the spike of a neuron 
+pattern being emitted in the synaptic cleft as a phase change in phase space that knocks another oscillator contributing to a phase pattern that the spike of a neuron 
 
  the change in the ion gradient is also linked to changes in the electric field, in terms of the fact that neurons fire multiple times before the ionic gradient is reset
 

a0041z.md

@@ -134,9 +134,7 @@ but back to LTD,
 
 so two neurons fire, at the same time, or close to the same time, because they are close in phase they each send signals to each other at the exact time when each of them is increasing it its interval of growth, everytime a neuron fires its interval of growth accelerates relative to neurons that did not fire at that moment in time, it becomes hotter for brief moment so there is a thermofield that is receiving a phase change
 
-holy shit
-
-What if the thermo field is time?
+Interesting idea: What if the thermo field was 1:1 correlated time? So that where time was sped up space was hotter. It's an interesting idea. What examples might break that idea?
 
 so it's like time accelerates around particles that have converged together in 3D space to oscillate in time, which causes the expansion of space.
 

a0053z.md

@@ -138,4 +138,9 @@ is introduced through the patch pipette."
 https://www.researchgate.net/publication/247089844
 DOI: 10.1016/S0304-3940(97)90197-X
 
-Not only are potassium channels key to APD, action potential duration, but they can be upregulated or downregulated by the signals they receive.
+Not only are potassium channels key to APD, action potential duration, but they can be upregulated or downregulated by the signals they receive.
+
+Listen to 2 audio recordings about this paper "Voltage-gated potassium channels are modulated by Fyn tyrosine kinase in Schwann cells"
+Regulation of potassium channels in myelin-forming glial cells
+Part 1 https://youtu.be/bCzWOtvMdFc
+Part 2 https://youtu.be/mQi3Smz0lGA