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single-cell-rna-sequencing

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RGC_Dnmt3a_pONC2d_paper

Retinal ganglion cells regeneration in 2 days post optic nerve crush retina | Lydia Tai | Dong Feng Chen Lab collaboration | Schepens Eye Research Institute, Mass General Hospital, Harvard Medical School

  • Updated Jun 24, 2024
  • R

This repository enables the reproducible analysis of an important developmental neuroscience dataset on hypothalamus neuron differentiation. It performs quality control, clustering, trajectory analysis, and identification of marker genes to characterize the differentiation trajectories of glutamatergic and GABAergic Onecut3+ neuronal subtypes.

  • Updated Aug 18, 2023
  • R

This project explores single-cell RNA sequencing (scRNA-seq) data using advanced machine learning techniques. By applying dimensionality reduction and graph-based models, we analyze high-dimensional scRNA-seq data to uncover cellular heterogeneity and reveal underlying biological processes at the single-cell level.

  • Updated Aug 14, 2024
  • Python

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